Publications

Decker L.M., Xiao H., Boone E.C., Vierling M.M., Shanker B.S., Kingston S.L., Boone S.F., Haynes J.B., and Shiu P.K.T. (2017) The nuclear cap-binding complex mediates meiotic silencing by unpaired DNA. G3 7: 1149-1155. [abstract] [pdf]

Decker L.M., Boone E.C., Xiao H., Shanker B.S., Boone S.F., Kingston S.L., Lee S.A., Hammond T.M., and Shiu P.K.T. (2015) Complex formation of RNA silencing proteins in the perinuclear region of Neurospora crassa. Genetics 199: 1017-1021. [abstract] [pdf]

Samarajeewa D.A., Sauls P.A., Sharp K.J., Smith Z.J., Xiao H., Groskreutz K.M., Malone T.L., Boone E.C., Edwards K.A., Shiu P.K.T., Larson E.D., and Hammond T.M. (2014) Efficient detection of unpaired DNA requires a member of the Rad54-like family of homologous recombination proteins. Genetics 198: 895-904. [abstract] [pdf]

Harvey A.M., Rehard D.G., Groskreutz K.M., Kuntz D.R., Sharp K.J., Shiu P.K.T., and Hammond T.M. (2014) A critical component of the meiotic drive in Neurospora is located near a chromosome rearrangement.  Genetics 197: 1165-1174. [abstract[pdf]

Hammond T.M., Xiao H., Boone E.C., Decker L.M., Lee S.A., Perdue T.D., Pukkila P.J., and Shiu P.K.T. (2013) Novel proteins required for meiotic silencing by unpaired DNA and siRNA generation in Neurospora crassa. Genetics 194: 91-100. [abstract[pdf]

Hammond T.M., Spollen W.G., Decker L.M., Blake S.M., Springer G.K., and Shiu P.K.T. (2013) Identification of small RNAs associated with meiotic silencing by unpaired DNA. Genetics 194: 279-284. [abstract] [pdf]

Hammond T.M., Rehard D.G., Xiao H., and Shiu P.K.T. (2012) Molecular dissection of the Neurospora Spore killer meiotic drive element. Proc. Natl. Acad. Sci. USA 109: 12093-12098. [abstract] [pdf]
*Commentary: Saupe, S.J. (2012) A fungal gene reinforces Mendel’s laws by counteracting genetic cheating. Proc. Natl. Acad. Sci. USA 109: 11900-11901. [abstract] [pdf]

Hammond T.M., Rehard D.G., Harris B.C., and Shiu P.K.T.(2012) Fine-­scale mapping in Neurospora crassa by using genome-­wide knockout strains. Mycologia 104:321-­323.[abstract] [pdf]

Hammond T.M., Xiao H., Boone E.C., Perdue T.D., Pukkila P.J., and Shiu P.K.T. (2011) SAD-3, a putative helicase required for MSUD, interacts with other components of the silencing machinery. G3 1: 369-376. [abstract] [pdf]

Hammond T.M., Xiao H., Rehard D.G., Boone E.C., Perdue T.D., Pukkila P.J., and Shiu P.K.T. (2011) Fluorescent and bimolecular-fluorescent protein tagging of genes at their native loci in Neurospora crassa using specialized double-joint PCR plasmids. Fungal Genet. Biol. 48: 866-873. [abstract] [pdf]

Xiao H., Alexander W.G., Hammond T.M., Boone E.C., Perdue T.D., Pukkila P.J., and Shiu P.K.T. (2010) QIP, an exonuclease that converts duplex siRNA into single strands, is required for Meiotic Silencing by Unpaired DNA. Genetics 186: 119-126. [abstract] [pdf]

FGB_coverAlexander W.G., Raju N.B., Xiao H., Hammond T.M., Perdue T.D., Metzenberg R.L., Pukkila P.J., and Shiu P.K.T. (2008) DCL-1 colocalizes with other components of the MSUD machinery and is required for silencing. Fungal Genet. Biol. 45: 719-727. Cover article. [abstract] [pdf]

Bardiya N., Alexander W.G., Perdue T.D., Barry E.G., Metzenberg R.L., Pukkila P.J., Shiu P.K.T. (2008) Characterization of interactions between and among components of the MSUD machinery in Neurospora crassa using Bimolecular Fluorescence Complementation. Genetics 178: 593-596. [abstract] [pdf]

Genetics_coverRaju N.B., Metzenberg R.L., and Shiu P.K.T. (2007) Neurospora Spore Killers Sk-2 and Sk-3 suppress Meiotic Silencing by Unpaired DNA. Genetics 176: 43-52. Cover article. [abstract] [pdf]

Bardiya N. and Shiu P.K.T. (2007) Cyclosporin A–resistance based gene placement system for Neurospora crassa. Fungal Genet. Biol. 44: 307-314. [abstract] [pdf]

Shiu P.K.T. and Glass N.L. (2006) Sequences important for heterokaryon incompatibility function in MAT A-1 of Neurospora crassa. Fungal Genet. Newsl. 53: 15-19. [abstract] [pdf]

PNAS_coverShiu P.K.T., Zickler D., Raju N.B., Ruprich-Robert G. and Metzenberg R.L. (2006) SAD-2 is required for Meiotic Silencing by Unpaired DNA and perinuclear localization of SAD-1 RNA-directed RNA polymerase. Proc. Natl. Acad. Sci. USA 103: 2243-2248. [abstract] [pdf]
*Commentary: Kelly, W.G. (2006) Standing guard: Perinuclear localization of an RNA-dependent RNA polymerase. Proc. Natl. Acad. Sci. USA 103: 2007-2008. [abstract] [pdf]

Shiu P.K.T. and Metzenberg R.L. (2002) Meiotic silencing by unpaired DNA: properties, regulation, and suppression. Genetics 161: 1483-1495. [abstract] [pdf]

Featured_ArticleShiu P.K.T., Raju N.B., Zickler D. and Metzenberg R.L. (2001) Meiotic silencing by unpaired DNA. Cell 107: 905-916. [Featured article] [abstract] [pdf]
*Commentary 1: Cogoni C. (2002) Unifying homology effects. Nat. Genet. 30: 245-246. [abstract] [pdf]
*Commentary 2: Kasbekar D.P. (2003) Sex and the single gene: Meiotic silencing by unpaired DNA. J. Biosci. 27: 633-635. [abstract] [pdf]
*Commentary 3: Hynes M.J. and Todd R.B. (2003) Detection of unpaired DNA at meiosis results in RNA-mediated silencing. Bioessays 25: 99-103. [abstract] [pdf]

Glass N.L., Jacobson D.J. and Shiu P.K.T. (2000) The genetics of hyphal fusion and post fusion recognition in filamentous ascomycete fungi. Annu. Rev. Genet. 34: 165-186. [abstract] [pdf]

Shiu P.K.T. and Glass N.L. (2000) Cell and nuclear recognition mechanisms mediated by mating type in filamentous ascomycetes. Curr. Opin. Micro. 3: 183-188. [abstract] [pdf]

Shiu P.K.T. and Glass N.L. (1999) Molecular characterization of tol, a mediator of mating-type-associated vegetative incompatibility in Neurospora crassa. Genetics 151: 545-555. [abstract] [pdf]

Saupe S., Stenberg L. , Shiu K.T., Griffith A.J.F. and Glass N.L. (1996) The molecular nature of mutations in the mt A-1 gene of the Neurospora crassa A idiomorph and their mating-type function. Mol. Gen. Genet 250: 115-122. [abstract] [pdf]